We are happy to inform you that we have introduced a new diagnostic assay for the analysis of lysosomal enzyme activities from Dried Blood Spots using Clinical Mass Spectrometry. This new assay will enable us faster turn-around times.
The assay was fully validated, and approved and accredited according to ISO 15189.
Please note that the cut-offs will change as follows:
Enzyme | old cut-off | new |
a-Galactosidase A for Fabry disease acid a-1,4-Glucosidase for Pompe disease acid Sphingomyelinase for Niemann-Pick A/B disease (ASMD) ß-Glucocerebrosidase for Gaucher disease |
>1.2 µmol/L/h >3.3 µmol/L/h >0.9 µmol/L/h
>2.5 µmol/L/h |
>2.8 µmol/L/h >2.0 µmol/L/h >1.2 µmol/L/h
>1.5 µmol/L/h
|
General information for you: The measurement of an enzyme activity and its cut-off is depending on substrates used, incubation temperature and time, and may differ from assay to assay, and lab to lab.
Please do not hesitate to contact us: info(at)archimedlife.com
Your ARCHIMED Life Science Team.